Synovial sarcoma was originally coined early in the 20th century as some thought that the microscopic similarity of some tumors to synovium and its propensity to arise adjacent to joints indicated a synovial origin; however, the actual cells from which the tumour develops are unknown and not necessarily synovial.
Primary synovial sarcomas are most common in the soft tissue near the large joints of the arm and leg but have been documented in most human tissues and organs, including the brain, prostate and heart.
Synovial sarcoma occurs most commonly in the young, representing about 8% of all soft tissue sarcomas but about 15-20% of cases in adolescents and young adults. The peak of incidence is before the 30th birthday and males are affected more often than females (ratio around 1.2:1).
Synovial sarcoma usually presents with an otherwise asymptomatic swelling or mass, although general symptoms related to malignicies can be reported such as fatigue.
Treatment usually involves: