DANI'S FOUNDATION: Fibrosarcoma

A fibrosarcoma is a malignant (cancerous) tumor that originates in the connective fibrous tissue found at the ends of bones of the arm or legs, and then spreads to other surrounding soft tissues. Soft tissues include fat, muscles tendons (bands of fiber that connect bones to muscle) nerves, joint tissue, blood vessels and other fibrous tissue. It most commonly affects either a lower leg or arm There are generally two forms of this disease:

Infantile or congenital fibrosarcoma: this type of tumor is the most common soft tissue sarcoma found in children under one year of age. It presents as a rapidly growing mass at birth or shortly after. This form of fibrosarcoma is usually slow-growing, and tends to be more benign than fibrosarcoma in older children, which behaves more like the type found in adults.
Adult form fibrosarcoma: The adult form of this disease can occur in older children and in adolescents, roughly between the ages of 10 and 15. It is more aggressive than the infantile form and generally involves more complex treatment.

What causes fibrosarcoma?

The exact cause of fibrosarcoma and other soft tissue tumors is not entirely understood, however, studies have indicated that genetic alterations may play a role. Researchers have studied a small number of families that contain several members from one generation who have developed soft tissue sarcomas. In addition, limited studies have shown a possible link between soft tissue sarcomas and the development of other types of cancer. A chromosomal rearrangement has been found in some fibrosarcomas.

What are the symptoms of fibrosarcoma?

The following are the most common symptoms of fibrosarcomas. However, each child may experience symptoms differently. The symptoms of fibrosarcoma vary depending on size, location and spread of the tumor. Symptoms may include:

A painless or tender mass in an extremity or trunk
Pain or soreness caused by suppressed nerves and muscles
Limping or other difficulty using legs, feet, arms hands

The symptoms of fibrosarcoma may resemble other conditions or medical problems. Always consult a physician for a diagnosis.

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